Neonatal metabolic and immunological states drive eosinophil infiltration in South American fur seal pups: Scripts

This dataset contains longitudinal physiological and immunological measurements from South American fur seal (Arctocephalus australis) pups monitored throughout early development on Guafo Island (northern Patagonia, Chile). Pups were sampled at birth, six weeks, and ten weeks of age, and then subjected to an inflammatory challenge with phytohemagglutinin (PHA) to quantify tissue eosinophil infiltration at ten weeks. The dataset includes metabolic, protein, and renal markers (e.g., cholesterol, total globulins, creatinine) together with eosinophil counts, allowing users to investigate how early-life metabolic context and contemporaneous physiological condition shape later eosinophilic responsiveness. Using these data, we fitted generalized linear models to test linear and quadratic relationships between metabolic variables and eosinophilic infiltration at the final stage, evaluating each variable separately within each developmental time point. The dataset and accompanying scripts enable reproduction of the original analyses as well as further exploration of developmental drivers of type 2 immunity in a free-ranging pinniped population under strong parasitic pressure.