TOTAL ARTIFICIAL HEART SYSTEM AND METHOD FOR PHASE-OFFSET CONTROL USING HIGH-FREQUENCY RIPPLE SPECTRAL CONTENT

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Authors: Duy Hoang Nguyen
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Abstract

This invention relates to a total artificial heart system having first and second rotary blood pumps configured to support systemic and pulmonary circulation, respectively, and a controller that regulates a non-zero relative phase offset between imposed pump cycles in order to reduce undesirable hemodynamic interference ripple. A sensed hemodynamic waveform, such as a pressure or flow waveform, is analyzed in the frequency domain by determining a fundamental frequency from pump command timing and separating spectral content into a baseline component at frequencies not greater than twice the fundamental frequency and a ripple-control component at frequencies above twice the fundamental frequency. The controller computes an interference ripple metric using only the higher-frequency component, holds the mean rotational-speed setpoints of the pumps fixed during evaluation, and updates the relative phase offset only when the ripple metric is reduced while mean-flow and mean-pressure targets remain within allowable ranges. In this manner, the invention selectively suppresses undesired high-frequency interference ripple while preserving desired baseline hemodynamic behavior and maintaining average circulatory performance.

Fields of Study & Subjects

Mechanical Circulatory Support Devices Tissue Engineering and Regenerative Medicine Congenital Heart Disease Studies

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
16 March 2026
Language
EN