Hypothesis: A Modular Antiviral Entry Blocking Platform Inspired by Natural Blood Group Antigen Resistance
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Host genetic variation can influence susceptibility to infection by modifying cell surface molecules used by pathogens for entry. A well-known example is the Duffy antigen receptor whose absence confers resistance to Plasmodium vivax malaria. Inspired by such natural resistance mechanisms, this paper proposes a conceptual antiviral strategy in which engineered molecules act as competitive blockers of viral attachment.
Fields of Study & Subjects
HIV Research and Treatment
interferon and immune responses
Virus-based gene therapy research
Publication details
- Journal / source
- Zenodo (CERN European Organization for Nuclear Research)
- Publication date
- 16 March 2026
- Language
- EN