Coherent Transport Advantage in Human Connectomes Re-emerges on Routing Motifs but Not at Whole-Brain Scale

Read full text
Authors: Oleg Dolgikh
Cited by: 2
References: 2

Abstract

Preprint of original research examining at what structural scale a coherent transport advantage remains detectable on human connectomes. Three analytical levels are tested: whole-brain (69 structure–function benchmarks), synthetic motif families, and weight-ranked routing subgraphs from 1,064 Human Connectome Project participants (Lausanne scale-125, 234 regions). Whole-brain analyses define the boundary of transfer; synthetic motifs reveal multiple ENAQT regimes and a timescale-matching principle (optimal dephasing rate scales with λ₂, Spearman ρ = 0.77); routing subgraphs show that structural predictability re-emerges at the motif scale, with T2 motifs dominated by target-side strength and T3 by source-corridor effective resistance. Effects survive FDR correction and control for direct source–target anatomy.

Fields of Study & Subjects

Functional Brain Connectivity Studies Advanced Neuroimaging Techniques and Applications Neural dynamics and brain function

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
25 March 2026
Document type
Preprint