MIXPRS+ polygenic score files for BMI and CAD

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Authors: Leqi Xu, Yikai Dong, Xiaowei Zeng, Zeyu Bian, Geyu Zhou, Leying Guan, Hongyu Zhao
Cited by: 1

Abstract

This dataset contains polygenic score (PGS) scoring files generated using the MIXPRS+ framework. Files included:- BMI_EAS_MIXPRSplus- BMI_AFR_MIXPRSplus- CAD_EAS_MIXPRSplus Each file is provided in gzipped tab-delimited text format (.txt.gz) and contains rsID, chromosome, base-pair position, effect allele, other allele, and effect weight (beta). All scores are based on genome build GRCh37. Related manuscript:Xu L, Dong Y, Zeng X, Bian Z, Zhou G, Guan L, Zhao H.Almost Free Enhancement of Multi-Population PRS: From Data-Fission to Pseudo-GWAS Subsampling.bioRxiv 2025.06.16.659952.https://doi.org/10.1101/2025.06.16.659952 This work has been accepted in principle at Nature Genetics with the updated title:MIXPRS enables multi-population and multi-method polygenic risk scores using summary statistics.

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
16 April 2026
Document type
Dataset