joonho345/Epilepsy_Rodent_Model_RNA: Cross-species transcriptomic analysis of rodent model fidelity to human mesial temporal lobe epilepsy

This repository contains the code used in the study: "Cross-species transcriptomic analysis of rodent model fidelity to human mesial temporal lobe epilepsy" Joonho Kim, Sangbo Lee, Bora Kim, et al. Nature Communications (2026) This release includes all bioinformatics pipelines and visualization scripts used for: RNA-seq processing (trimming, alignment, quantification) Batch correction Human integrative analysis Cross-species transcriptomic correlation analysis Gene set enrichment analysis (GSEA) Overrepresentation analysis (ORA) Cell type deconvolution Figure generation Data availability: Human RNA-seq data: SRA (PRJNA280563, PRJNA290212, and others listed in manuscript) Rodent RNA-seq data: SRA (PRJNA215950, PRJNA293972, and others listed in manuscript) Intra-amygdala kainate model data: SRA (PRJNA1425071)