Study 54 — Ramadan Intermittent Fasting as a Population-Scale Natural Experiment in Autoimmune Disease
Abstract
Study 54 of the Hidden Infections research series. Systematic evidence synthesis evaluating Ramadan intermittent fasting (12-18h daily, 28-30 days) as a population-scale natural experiment in autoimmune disease across six conditions. Key findings: RA — STRONG (DAS28 reduction, 5+ independent cohorts, n=240 largest); PsA — STRONG (weight-loss-independent benefit, multicentre n=37); SpA, IBD, MS, SLE — MODERATE. Cytokine meta-analysis (n=522, 14 studies): IL-6 SMD -0.68 (p
Fields of Study & Subjects
Dietary Effects on Health
Immune responses and vaccinations
Genetics
Aging
and Longevity in Model Organisms
Publication details
- Journal / source
- Zenodo (CERN European Organization for Nuclear Research)
- Publication date
- 24 June 2026
- Document type
- Preprint