HAA_eQTL: Code and processed data for blood eQTL analysis of high-altitude adaptation

This repository contains analysis scripts, processed association results, and figure code from a whole-blood eQTL study of high-altitude adaptation. The study cohort comprised 61 native highlanders (NHs) and 164 acclimatized newcomers (ANs), for a total of 225 participants. The analyses covered cis- and trans-eQTL mapping, cell type interaction eQTLs, eQTL hotspot detection, cross-population agreement, stratified LD score regression, Mendelian randomization, colocalization, and transcriptome-wide association analysis. Raw WGS and RNA-seq data are available at https://ngdc.cncb.ac.cn/gsa-human/ under controlled access at HRA009343.