Guiding Large Language Models to Predict Edit Sequences for Molecular Synthesizability Optimization

Zenodo (CERN European Organization for Nuclear Research) 2026 Open access

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Authors: Junren Li, Luhua Lai
DOI: 10.5281/zenodo.21869222
Cited by: 1

Abstract

SynCraft is a reasoning-based framework that leverages Large Language Models to optimize molecular synthesizability through minimal atomic edits. This repository contains the complete implementation including the edit executor, few-shot retrieval system, and interaction-aware prompting module.

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
10 August 2026