Perioperative Use of Benzodiazepines in Orthopedic Surgery: A Brief Narrative Review

Orthopedic Reviews 2026 Open access

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Authors: Anvinh Nguyen, Joseph Donnelly, Tommy Li, Jamal J. Hasoon
DOI: 10.52965/001c.158573
Cited by: 0
References: 15

Abstract

Benzodiazepines are frequently administered in orthopedic anesthesia for anxiolysis, sedation, amnesia, and seizure prophylaxis. Their role continues to evolve with the growing use of regional anesthesia, outpatient joint procedures, and enhanced recovery after surgery (ERAS) pathways. This narrative review examines the pharmacology, mechanisms of action, clinical indications, contraindications, and key clinical studies of benzodiazepines commonly used in the operating room in the United States, with a specific focus on their application in orthopedic surgical practice.

Fields of Study & Subjects

Anesthesia and Sedative Agents Anesthesia and Pain Management Intensive Care Unit Cognitive Disorders

Publication details

Journal / source
Orthopedic Reviews
Volume
18
Pages
158573–158573
Publication date
13 March 2026
Language
EN