Factors Related to Mortality in Critically Ill Patients Hospitalized with Gastrointestinal Hemorrhage: A Cross-sectional Study from a University Hospital

Objective: This study aims to ascertain the demographic characteristics, comorbidities, fundamental laboratory data and mortality predictors of patients with gastrointestinal (GI) bleeding admitted to the intensive care unit (ICU) by the application of scoring methods.Material and Methods: Data of patients followed up in Akdeniz University Hospital Internal Medicine ICU between June 2019 and December 2023 were retrospectively reviewed. The Acute Physiology and Chronic Health Evaluation (APACHE)-II and Sequential Organ Failure Assessment (SOFA) scores of the patients were recorded within the initial 24 hours of ICU admission. The quantities of blood product replacements, laboratory findings, lactate concentrations, and endoscopic data were analyzed. The statistics were compared between the groups of survival and non-survival (deceased) patients.Results: The study included 95 patients. The mortality rate in these patients was determined as 29.47%. The international normalized ratio (INR) and lactate levels of patients were found to be predictive of in-hospital mortality. Lactate and INR levels were markedly elevated in the mortality group, with an hazard ratio (HR) of 1.29 (95% confidence interval [CI]: 1.13-1.46, p