Can the Development and Recurrence of Uveitis in Behçet’s Disease be Predicted? Which Predictors Are at the Forefront?

ABSTRACTObjectiveOne of the main manifestations of Behçet's disease (BD) with the highest morbidity rate is uveitis. Uveitis recurrence (UR) rate is still high and can cause significant physical and mental distress in patients with BD, and prolonged treatment is also a major financial burden. We aimed to determine the factors predicting the developmentand recurrence of uveitis and to calculate the time to development and recurrenceof uveitis.Material and MethodsIn a two-center retrospective study, a total of 78 BD patients who met the internationalcriteria for Behçet’s disease (ICBD), 41 patients with uveitis and 37 patients without uveitis, were included.ResultsThe absence of genital ulcer (GU) alone was found to be an independent factor with 65.3% probability of the development of uveitis (DoU). The rate of predicting DoU was 72.2% when the prolonged time to diagnosis and the absence of GA were combined. In patients with a body mass index (BMI) of 25 kg/m2, the risk of UR was 70%.ConclusionTwo main findings of this study were that uveitis and UR were more common in patients without GU and with high BMI, respectively.