Gut Microbiota and Systemic Inflammation: Implications for Cardiovascular and Metabolic Diseases

African Journal of Biomedical Research 2026 Open access

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Authors: Sylwester Szymon Stawowski, Ada Kondrat, Urszula Rusiłowicz, Gabriel Mandera, Jakub Plewik, Agata Sowińska-Pelak, Kinga Rydel, Zuzanna Sojko, Katarzyna Szurna, Urszula Miłkowska, Paweł Mierzejewski, Wojciech Franciszek Majewski
+7 more Emilia Lenkiewicz, Julia Komar, Hubert Chmielewski, Zuzanna Twarowska, Agata Sowińska-Pelak, Aleksandra Katarzyna Zięba, Monika Mysera
DOI: 10.53555/ajbr.v29i1s.9212
Cited by: 0

Abstract

The gut microbiota is a key regulator of metabolic, immune, and inflammatory processes. Growing evidence suggests that dysbiosis contributes to systemic low-grade inflammation, a central mechanism underlying cardiovascular and metabolic diseases. Increased intestinal permeability and translocation of microbial-derived components may activate inflammatory pathways and promote metabolic dysfunction. This narrative review summarizes current evidence on the role of gut microbiota in systemic inflammation and discusses its implications for cardiovascular and metabolic disorders.

Fields of Study & Subjects

Gut microbiota and health Oral microbiology and periodontitis research Adipokines Inflammation and Metabolic Diseases

Publication details

Journal / source
African Journal of Biomedical Research
Volume
29
Issue
1
Publication date
1 January 2026
Language
EN