A Rare Cause of Spontaneous Pneumothorax: Invasive Pulmonary Aspergillosis in an Immunocompetent patient.

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Authors: Dr. Deepakchandar N, Nivethitha K. S, Chandrasekar C., Dr. Balamurugan S, Dr. Manoj. R, Dr. Manikandan. N
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Abstract

Introduction: Invasive pulmonary aspergillosis (IPA) is a life-threatening fungal infection caused primarily by Aspergillus species, most commonly Aspergillus fumigatus. It typically affects the lungs, leading to tissue invasion, necrosis, and cavitary lesions. IPA usually presents with nonspecific respiratory symptoms such as cough, dyspnea, hemoptysis, and fever, along with radiological findings like consolidations, nodules, or cavitations. While these manifestations are well-documented, spontaneous pneumothorax as a presentation of IPA is extremely rare. The pathophysiology of pneumothorax in the context of IPA is thought to involve rupture of necrotic or cavitary lung tissue into the pleural space, resulting in air leak. Due to its infrequent occurrence, IPA-related pneumothorax is often overlooked, which can delay diagnosis and timely initiation of antifungal therapy. Recognizing this unusual presentation is crucial for clinicians, as early identification and management significantly influence patient outcomes and reduce associated morbidity and mortality.

Fields of Study & Subjects

Antifungal resistance and susceptibility Pleural and Pulmonary Diseases Fungal Infections and Studies

Publication details

Journal / source
African Journal of Biomedical Research
Publication date
1 January 2026
Language
EN