Increased Risk of Complications in Total Hip Arthroplasty (THA) of Femoral Neck Fracture (FNF): A Comparative Meta-Analysis of THA Outcomes in FNF and Osteoarthritis

Despite contradictory results of various published data on the subject, the complications of total hip arthroplasty (THA) in femoral neck fracture (FNF) compared to those in osteoarthritis (OA) are yet to be further elucidated.We queried PubMed, Cochrane, and Google Scholar from inception until October 2024 for studies that compared the surgical outcomes of THA in the management of FNF and OA.We evaluated the overall complications, such as dislocations, prosthetic joint infection (PJI), intraoperative fractures, periprosthetic fractures (PPFx), mechanical loosening, venous thromboembolism (VTE), hematoma, leg length discrepancy (LLD), and revisions.In addition, surgical parameters such as the duration of surgery and the length of stay (LOS) were also assessed.Eleven studies were included in our meta-analysis.The use of THA in FNF is associated with high risks of overall complications (odds ratio [OR] 1.58, 95% confidence interval [CI] 1.00-2.49,P=0.05), dislocations (OR 2.12, 95% CI 1.07-4.21,P=0.03), PJI (OR 1.75, 95% CI 1.50-2.05,P