Bilateral Amyloid Arthropathy of the Hip Joint Presented with Pathologic Fracture in a Hemodialysis Patient: A Case Report

Hip fractures, primarily observed in elderly and frail people, significantly reduce the quality of life due to chronic pain and limited mobility with a prolonged recovery period.The risk of mortality associated with hip fractures is high immediately post-surgery and remains elevated for up to a year.Pathological fractures arise in bones compromised by underlying conditions.Bone fractures of the hip can severely impact the rates of morbidity, survival, and the overall quality of life 1) .Pathological fractures of the hip may be caused by several factors, such as metastatic disease, primary bone tumors, osteoporosis, osteomalacia, infections, and amyloidosis, among others 2,3) .Amyloid arthropathy is a disease often observed in patients undergoing dialysis where tissues display an abnormal accumulation of amyloid.In long-term dialysis patients, amyloid arthropathy typically results from an accumulation of the beta-2 microglobulin protein because it cannot be effectively removed by the kidneys.Amyloid arthropathy can lead to arthritis-like symptoms in joints, particularly in major joints like the hip.In severe cases, it progresses to osteolysis and pathological fractures 4) .This case report highlights a rare instance of bilateral hip amyloidosis that leads to pathological fractures in a long-term dialysis patient.Through our report, we emphasize the importance of early detection and management of amyloid arthropathy.This is the first such case reported in Korea, which underscores the need for heightened clinical awareness regarding hip pain in