Potential Effect of Samwa (Cleome Droserifolia) Plant on Hepatointoxication Rats

The present study aims to investigate the potential effect of different concentrations of 2.5, 5 ,7.5 and 10% Samwa as powder on Hepatointoxication complications in rats. thirty-six male albino rats, weighing 150±10 g, were used and divided into two main groups. The first group, 6 rats, was kept as a negative (-ve) control group fed on the basal diet while the second one, 30 rats, was injected by Carbon tetrachloride (Ccl4) to induce Hepatointoxication and divided into five equal sub groups. The second group was still fed on the basal diet and kept as positive (+ve) control group and the rest four groups were fed on the basal diet containing 2.5, 5, 7.5 and 10% of Samwa powder. Serum liver function (ALT, AST, ALP). kidney function (urea, creatinine, uric acid), Albumin, Total protein and histopathological changes of liver was examined the obtained results concluding that the feeding with the tested plant improved the kidney functions, liver functions specially the high concentrate of these studied plant used. All of these effects could be principally attributed to the strong antioxidant activities of these plant parts as the result of their high bioactive compounds content. These findings provide a basis for the use of Samwa plant for the treatment of complications caused by Hepatointoxication.