Ameliorative Effects of Borreria verticillata aqueous extract on Adenium obesum Stem Bark aqueous extract induced toxicity on the Hematological Profile of Clarias gariepinus (Burchell 1822) juveniles

The present study was carried out to determine the effect of Borreria verticillata aqueous extract on Adenium obesum stem bark extract-induced hematological alterations in juveniles of Catfish. The study consisted of one hundred and fifty (150) Clarias gariepinus juveniles randomly distributed into ten (10) groups of fifteen (15) fish per group. G1 (control) received no treatment, Groups 2, 3, 4and 5 received 25, 50, 100, 200 mg/L of the Borreria verticillata aqueous extract (BVAE) respectively for 28 days. Group 6 received 0.838 mg/L of Adenium obesum extract (AOE) only for 28 days, which is 10%LC50 of AOE. Groups 7,8,9 and10, received the combinations of the extracts, first the 10%LC50 AOE followed by 25 mg/L BVAE, 50 mg/L BVAE, 100 mg/L and 200 mg/L BVAE, respectively). Red blood cell (RBC), hemoglobin concentration (Hb) and packed cell volume (PCV) were significantly (P < 0.05) lower in Group 6 (10% LC50 AOE) when compared to the corresponding values in the groups (7-10) exposed to AOE and treated with BVAE. The mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH) and mean corpuscular hemoglobin concentration (MCHC) were significantly (P < 0.05) lower in group 6 when compared to the groups (7-10) that were exposed to AOE and treated with BVAE. The total white blood cells count was significantly (P