Understanding drug-induced hyperthermia
Abstract
Drug-induced hyperthermia encompasses a spectrum of potentially life-threatening syndromes caused by pharmacological agents. This review summarizes the current understanding about the disease pathophysiology, clinical manifestations, diagnostic challenges, and therapeutic strategies. Emphasis is placed on major syndromes, including neuroleptic malignant syndrome, serotonin syndrome, malignant hyperthermia, anticholinergic toxicity, and sympathomimetic toxicity. Early recognition and timely intervention are crucial for reducing morbidity and mortality.
Fields of Study & Subjects
Electroconvulsive Therapy Studies
Thermal Regulation in Medicine
Poisoning and overdose treatments
Publication details
- Journal / source
- Clinical Critical Care
- Volume
- 34
- Pages
- e260005–e260005
- Publication date
- 11 February 2026
- Language
- EN