Multi-marker Enrichment Enhances the Sensitivity of Electrochemical Sensing Technology for Breast Cancer Detection

Breast cancer is one of the most common cancers, and early detection is crucial for improving patient survival. However, conventional imaging and serum-based diagnostic methods still suffer from limited sensitivity or limited applicability in early-stage detection. In recent years, biomarker-based detection approaches have been widely applied in breast cancer diagnosis and have improved detection accuracy to some extent. Nevertheless, single-biomarker detection is often insufficient to reflect the high heterogeneity of breast cancer, which may lead to inaccurate diagnostic results. In this article, the diagnostic accuracy of single-biomarker detection and multi-biomarker detection is compared. The results show that multi-biomarker detection can significantly increase detection accuracy by providing more comprehensive molecular information. By analyzing multiple biomarkers simultaneously, diagnostic reliability can be improved and the risk of false results can be reduced. In order to achieve highly sensitive and low-cost detection, electrochemical biosensing technology is introduced for multi-biomarker detection. Due to its high sensitivity, fast response, simple operation, and low cost, electrochemical biosensing technology shows great potential for efficient and accurate breast cancer detection.