Squamous Cell Carcinoma of the Nasal Cavity: A Case Report

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Authors: Jeilani ould Abdel Baghi, Moad El Mekkaoui, Zakaria El Hafi, Zakaria Arkoubi, Razika Bencheikh, Mohamed Anass Benbouzid, Leila Essakalli
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Abstract

Squamous cell carcinoma (SCC) of the nasal cavity is a rare and aggressive malignancy within the spectrum of sinonasal tumors. Owing to its nonspecific early symptoms, diagnosis is frequently delayed, leading to locally advanced disease at presentation. We report the case of a 46-year-old male patient with type 2 diabetes mellitus who presented with progressive right-sided nasal obstruction evolving over seven months, associated with intermittent mild epistaxis. Nasal endoscopy revealed a friable mass arising from the right middle meatus. Radiological evaluation with computed tomography (CT) and magnetic resonance imaging (MRI) demonstrated a localized nasal cavity tumor without significant bony destruction or distant extension. Histopathological examination confirmed a moderately differentiated squamous cell carcinoma. The patient underwent extended endoscopic surgical resection followed by adjuvant radiotherapy. Postoperative recovery was uneventful, and no evidence of recurrence was observed during follow-up. This case highlights the diagnostic challenges, therapeutic considerations, and prognostic factors associated with nasal cavity SCC and emphasizes the importance of early detection and multidisciplinary management.

Fields of Study & Subjects

Head and Neck Surgical Oncology Head and Neck Cancer Studies Nasal Surgery and Airway Studies

Publication details

Journal / source
International Journal of Recent Development in Engineering and Technology
Volume
15
Issue
1
Pages
1061–1065
Publication date
30 January 2026