Mesenchymal Chondrosarcoma of the Naso-Sinus Region: A Case Report

Mesenchymal chondrosarcoma (MCS) of the naso-sinus region is an uncommon malignant tumor characterized by aggressive local behavior and a high risk of recurrence. Representing less than 0.5% of paranasal sinus neoplasms, it poses diagnostic and therapeutic challenges due to its rarity and nonspecific early presentation. We report the case of an 18-year-old male with persistent right nasal obstruction and intermittent epistaxis whose histopathological diagnosis confirmed a mesenchymal chondrosarcoma of the naso-sinus region. This report offers a detailed description of the clinical features, endoscopic findings, imaging characteristics, histopathological evaluation, therapeutic approach, and outcome. A comprehensive review of the literature is also presented to contextualize this case within current scientific knowledge and to highlight key diagnostic and therapeutic insights