Wound Closure Techniques: Subcuticular Vs Interrupted Transdermal Sutures in Paediatric Patients Undergoing Open Appendectomy for Complicated Appendicitis: A Randomized Controlled Trial
Abstract
Paediatric patients who undergo open appendectomy for complicated appendicitis face risks of surgical site infections (SSIs) and poor wound healing. Objectives: To compare continuous subcuticular versus interrupted transdermal sutures to determine their effects on SSI rates, scar cosmesis, and overall wound healing. Methods: A randomized controlled trial (TCTR20250527004) was conducted from September 2024 to March 2025, enrolling patients aged ≤12 with complicated appendicitis. Patients of both genders aged up to 12 years presenting to the paediatric surgery emergency with acute appendicitis grade 2 and above. Patients were randomized equally into two groups: Group A (continuous subcuticular closure) and Group B (interrupted transdermal closure). Primary outcomes were SSI, wound dehiscence, and Manchester Scar Scores up to 30 days post-op. Statistical analysis was done using SPSS version 23.0, with t-tests and logistic regression. Results: A total of 112 patients were included in the study, with 56 in each group. The mean number of patients with surgical site infection (SSI) in group A was 1.30 ± 0.46, and in group B mean SSI was 1.37 ± 0.49, with a p value of 0.43. However, the grade of appendicitis was a significant predictor of infection, with higher grades correlating with increased odds of infection (OR=1.83, p
Fields of Study & Subjects
Surgical Sutures and Adhesives
Appendicitis Diagnosis and Management
Surgical site infection prevention
Publication details
- Journal / source
- Pakistan Journal of Health Sciences
- Pages
- 20–26
- Publication date
- 31 January 2026