Quality of life among patients with peptic ulcer disease at Danang Hospital in 2025

Objective: To describe the quality of life and identify factors associated among inpatients with peptic ulcer disease at the Department of Gastroenterology, Da Nang Hospital in 2025. Methods: A cross-sectional descriptive study was conducted on 114 inpatients aged ≥ 18 years diagnosed with peptic ulcer disease via endoscopy. The Vietnamese version of the Quality of Life Instruments for Chronic Diseases – Peptic Ulcer (QLICD-PU) was used for face-to-face interviews one day prior to discharge. Data were analyzed using descriptive statistics and association analysis (OR, 95% CI, p < 0.05). Results: The mean overall quality of life score was 49.34 ± 8.93. Domain scores were psychological (58.25 ± 13.41), social (51.81 ± 9.80), symptom-specific (44.67 ± 8.73), and physical (42.54 ± 15.58). QoL levels were classified as good (50.0%), moderate (49.1%), and poor (0.9%). The quality of life was significantly associated with age, income, disease duration, history of hospitalization, comorbidities (cardiovascular and musculoskeletal), smoking, and alcohol consumption (p < 0.05). Conclusion: The quality of life of patients with peptic ulcer disease was predominantly at an moderate to good level. Clinical interventions should prioritize counseling and support for older patients, those with low income, prolonged disease duration, and co-existing chronic conditions to improve their overall quality of life.