Effect of a combined of positive emotion, engagement, relationships, meaning, and accomplishment-based mental health intervention and role model incentives

BACKGROUND Patients with ovarian cancer often experience significant psychological stress during chemotherapy, including emotional disorders such as anxiety and depression. AIM To analyze the application value of positive emotion, engagement, relationships, meaning, and accomplishment (PERMA) well-being care combined with role model motivation in patients with ovarian cancer undergoing chemotherapy for anxiety and depression, with a focus on psychological health and compliance behavior. METHODS Seventy patients with ovarian cancer undergoing chemotherapy were recruited from a hospital between August 2022 and August 2024. They were randomly divided into two groups using a lottery method: The reference group (n = 35, receiving routine care) and the experimental group (n = 35, receiving PERMA well-being care combined with role model motivation in addition to routine care). Both groups received their respective interventions before and after chemotherapy. Psychological state, mood state, compliance behavior, and cancer-related fatigue levels were assessed before and after the intervention. Data were analyzed using the SPSS software (version 26.0). RESULTS After the intervention, patients’ psychological state scores improved, with the experimental group showing better scores than the reference group (P < 0.05). After the intervention, both groups’ mood state scores decreased in most dimensions, except for increased vigor, with the experimental group showing a greater improvement (P < 0.05). Compliance was higher in the experimental group than in the control group (P < 0.05). Cancer-related fatigue scores decreased in both groups after the intervention, with the experimental group having lower scores than the reference group (P < 0.05). CONCLUSION PERMA well-being care combined with role model motivation is effective in reducing anxiety and depression symptoms, improving mood states, enhancing compliance behavior, and alleviating cancer-related fatigue in patients with ovarian cancer undergoing chemotherapy for anxiety and depression. Therefore, this approach warrants broader clinical application.