Effect of multidisciplinary closed-loop care on pregnancy outcomes in anxiety and depression

BACKGROUND Perinatal anxiety and depression are prevalent conditions associated with significant health risks. Investigating the efficacy of a multidisciplinary approach combined with a closed-loop psychological intervention is essential for improving related outcomes. AIM To evaluate the clinical value of a multidisciplinary closed-loop intervention in improving pregnancy outcomes and promoting postpartum recovery in pregnant women with anxiety and depression. METHODS We conducted a randomized controlled trial involving 240 pregnant women with anxiety and depressive symptoms who received regular prenatal care at Shanghai Songjiang Maternal and Child Health Hospital between January 2024 and January 2025. Participants were randomized to an intervention group (multidisciplinary closed-loop intervention) or a control group (routine care). Delivery outcomes, maternal and neonatal complications, and postpartum pelvic floor function were compared. RESULTS The intervention group exhibited significantly lower rates of cesarean section (31.7% vs 44.2%, P < 0.05), adverse maternal outcomes (15% vs 32.5%, P < 0.01), and adverse neonatal outcomes (6.7% vs 15.8%, P < 0.05). Additionally, the intervention group demonstrated higher rates of normal labor progression (96.3% vs 86.5%, P < 0.05) and intact perineum (50.0% vs 32.8%, P < 0.05), alongside superior pelvic floor muscle recovery. CONCLUSION This integrated multidisciplinary closed-loop intervention model effectively improves maternal and infant outcomes and enhanced postpartum recovery in women experiencing perinatal anxiety and depression.