Long-term behavioural and neurochemical alterations following in utero co-exposure to aluminium and cadmium in mice.

▪ Industrialization and mineral exploration activities remains the greatest contributors to metal pollution and contamination worldwide.▪ However, low-income earners in communities hosting these activities bear a greater burden of the adverse effects of heavy metal pollution.▪ While early life metal exposure during pregnancy has been linked to several neurodevelopmental disorders, ▪ Understanding the key biological mechanisms of the effect of two or multiple metal toxicants during pregnancy on neurodevelopmental outcomes remain elusive.▪ To investigate the behavioural and biochemical responses of male mice co-exposed to in-utero aluminum and cadmiumBehavioral analysis, EPM, LDT.