Conversion of Benzene to Benzanilide via Beckmann Rearrangement

International Journal of Creative and Open Research in Engineering and Management 2026 Open access

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Authors: Dr. Naimish Kumar Verma
DOI: 10.55041/ijcope.v2i3.046
Cited by: 0

Abstract

Benzanilide (C₆H₅–CO–NH–C₆H₅) is an aromatic amide widely used in pharmaceutical and organic synthesis. A convenient synthetic route involves the Beckmann rearrangement of acetophenone oxime. This study presents a stepwise method starting from benzene, detailing the preparation of acetophenone via Friedel–Crafts acylation, formation of acetophenone oxime, and subsequent rearrangement to benzanilide under acidic conditions.

Fields of Study & Subjects

Chemical Synthesis and Reactions Organic and Inorganic Chemical Reactions Chemical synthesis and pharmacological studies

Publication details

Journal / source
International Journal of Creative and Open Research in Engineering and Management
Volume
02
Issue
03
Pages
1–9
Publication date
12 March 2026
Language
EN