Enhancing the Availability, Assimilation, and Accessibility of Bioactives through Nanoencapsulation

ABSTRACT: Bioactive compounds are secondary metabolites secreted by plants and plant derived products which are essential for human health. Because bioactive chemicals have the potential to maximize therapeutic efficacy and minimize side effects, there has been a lot of attention focused on developing effective delivery systems for these compounds in recent years. One method that has shown promise for overcoming the difficulties in delivering bioactive substances is nanoencapsulation. The state-of-the-art in bioactive compound delivery systems using nanoencapsulation is thoroughly reviewed in this paper. Present review deals with the brief study of bioactive delivery and their improvement for better biostability via nanoencapsulation. Nanotechnology holds potential perspectives for food processing, including superior antimicrobial effects, improved sensory quality and safety, enhanced nutrient bioavailability in food preparations, and targeted delivery and controlled release of bioactive ingredient along the gastrointestinal tract. The review commences with an explanation of the principles of nanoencapsulation, covering different methods for encapsulating bioactive substances in nano-sized carriers, including coacervation, emulsification, and nanoprecipitation. The benefits of nanoencapsulation are also emphasized, including enhanced solubility, stability, bioavailability, and targeted distribution. Keywords: Nanoencapsulation, bioactive compounds