Natural Plant-Derived Interventions in Burn Wound Healing: Mechanistic Insights

Abstract: Burn injury causes structural and functional damage to tissues which remain the major global health issue as thousands of cases are reported annually. Conventional treatment including silver nitrate, silver sulfadiazine, mafenide and other antibiotics which are used topically have some adverse effects such as hypersensitivity, scar formation and incomplete healing which make treatment less effective. As a result, more attention was shifted towards the use of herbal remedies which offers potential healing property. This literature mainly focuses on therapeutic potential of aloe-vera, Chenopodium album, Praecitrullus fistulosus in burn management. These plants are rich in phytochemical constituents which posse’s anti-inflammatory, anti-oxidant and wound healing properties. The extract of these plants contains terpenoids, tannins, flavonoids and phenolic compounds which are responsible for accelerating burn wound healing, enhance tissue repair and reduce oxidative stress. The burn cream which can formulated using these herbal plants is a beneficial alternative to conventional burn treatment. The discussion shows the effectiveness of this herbal ingredients in burn treatment hence it shows fewer side effects compare to synthetic burn cream. KEYWORDS: Burn wound, aloe-vera Chenopodium album, praecitrullus fistulosus