In Vivo And In Vitro Toxicity of Binary Combination of Column Purified Fraction of Asparagus Racemosus and Glycyrrhiza Glabra Against the Sporocyst, Redia and Cercaria Larva of Fasciola Gigantica

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Authors: Departmrnt of Zoology, Doodhnath Singh Smarak Mahavidyalaya Mariahu, Jaunpur U.P. 222161, Vishwakarma A. K., Ravikash Maurya, Dr. Pradeep Kumar
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Abstract

In binary combination (1:1) of the activity of A. racemosus and G. glabra against Fasciola gigantica larva in Lymnaea acuminate observe in vivo and in vitro experiments, which is based on time and concentration-dependent toxicity. In vivo treatment represent the highest toxicity against cercaria larva, with 2Hr LC50 and 8Hr LC50 of A. racemosus and G. glabra at 64.85 mg/L and 39.78 mg/L, respectively while in in vitro treatment the toxicity against sporocyst larva, with 2Hr and 8Hr LC50 values of 64.59 mg/ml and 46.27 mg/ml, respectively. Negative regression between exposure period and LC50 is significant (p1.96, and g values

Fields of Study & Subjects

Helminth infection and control Mollusks and Parasites Studies Parasites and Host Interactions

Publication details

Journal / source
International Scientific Journal of Engineering and Management
Volume
05
Issue
02
Pages
1–9
Publication date
13 February 2026
Language
EN