Chemotherapy-Induced Lung Disease: A Case Series

Chemotherapy-induced lung disease (CILD) is a serious complication that can negatively impact quality of life.It usually presents with inflammation and interstitial fibrosis, accompanied by symptoms ranging from mild dyspnea and cough to severe respiratory failure.Diagnosis is challenging, as it is often confused with infections or other interstitial lung diseases, as bronchoalveolar lavage results are usually nonspecific.We retrospectively evaluated eight CILD cases that were treated in our clinic between 2023 and 2024.Most patients had pulmonary symptoms, and thoracic CT scans often showed bilateral ground-glass opacities.Most patients improved clinically and radiologically after chemotherapy was halted and methylprednisolone treatment initiated, although some did not survive, especially those with additional comorbidities.Timely diagnosis and management are crucial in reducing morbidity and mortality in affected patients.This case series aims to raise awareness about CILD and to emphasize the importance of a multidisciplinary approach to avoid misdiagnosis and unnecessary treatment.