Exploring the relationship between loneliness, social isolation and health
Abstract
This triangulation study examined whether there was evidence of causal effects of loneliness and social isolation on a range of general health, physical health and mental health and wellbeing outcomes. We conducted observational, sibling design, one-sample and two-sample Mendelian randomisation (MR) analyses using publicly available GWAS data and data from UK Biobank. The analysis plan for this study was pre-registered (https://osf.io/gwpny).
Publication details
- Journal / source
- Bristol Research (University of Bristol)
- Publication date
- 1 January 2026
- Language
- EN
- Document type
- Dataset