Experimental infection of horses with African horse sickness virus results in overt disseminated intravascular coagulation

This was a prospective, descriptive study where four horses were experimentally infected with AHSV. Blood samples were obtained before infection, then every 24 hours until humane euthanasia. Haematology and thromboelastography (TEG) was performed and prothrombin time (PT), activated partial thromboplastin time (aPTT), fibrinogen and D-dimer concentrations, as well as activities of antithrombin (AT) and coagulation factors II, VII, VIII, X, and XII were measured.