Prescription Pattern of Immunosuppressants Used in Post-Transplant Patients

Organ transplantation is a life-saving medical operation in which a healthy graft from a donor is used to replace a failing or diseased organ. Maintaining graft survival and preventing allograft rejection require lifelong immunosuppressive treatment. The purpose of this retrospective observational study was to examine the immunosuppressive medication prescription trend among post-transplant patients at a Bengaluru tertiary care facility. Over the course of 6 months, 107 prescriptions were examined. The greatest-age group was 41-50 years old (32.7%), with men making up most patients (81.7%). Tacrolimus, prednisolone, and mycophenolate mofetil was the most often given combination (22.4%), followed by tacrolimus, mycophenolate sodium, and prednisolone, 18.7%. Tacrolimus alone was prescribed to 6 patients (5.6%) for maintenance therapy, whereas dual therapy was less prevalent, with tacrolimus and prednisolone, 6.5% being the most common combo. The study comes to the conclusion that triple immunosuppressive medication is still the recommended method for post-transplant care and that organ transplantation was more common in men. Because of its efficacy and safety, tacrolimus remains the mainstay medication in both single and combo regimens.