Nanoemulgel technology for cosmeceutical advancements: a synergy of therapy and beauty

Nanoemulgel is a hybrid formulation composed of nanoemulsion and a gelling agent. The nanoemulsion incorporate the benefit of natural oil and the therapeutic effect of active pharmaceutical ingredient. The presence of a gelling agent enhances the contact time with skin layer. It offers a new way to enhance both therapeutic effectiveness and aesthetic performance. Nanoemulgel, apart from increase drug retention it also enhances solubility, and skin penetration, with gel like consistency. It is topically applied for various therapeutic purpose in various skin diseases such as psoriasis, candidiasis etc. Now a days it emerged as a potential cosmeceutical product for anti-ageing, pigmentation, acne management, UV protection, and nourishment. Preference to natural bioactive in nanoemulgel formulations makes it environmentally friendly and sustainable formulations. In recent years, the formulation development with advanced evaluation methods has reported precise therapeutic accuracy with enhanced safety profiles and performance of the nanoemugel formulations. Beside these advantages, the long-term stability, large-scale manufacture, and regulatory approval are still challenging. The invention of multifunctional cosmeceutical preparations that smoothly combine treatment and cosmetic improvement has advanced significantly through the advent of nanoemulgel technology.