Acquired generalised lipodystrophy as an uncommon complication of anti-Mi-2 dermatomyositis: a case report

Clinical and Experimental Rheumatology 2026 Open access

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Authors: Antonio Bustos-Merlo, Marı́a Martı́n-Armada, Mónica Zamora‐Pasadas, Isabel Sánchez-Berná, Nuria Navarrete‐Navarrete
DOI: 10.55563/clinexprheumatol/0mkobh
Cited by: 0
References: 5

Abstract

Clinical manifestations of acquired generalised lipodystrophy in an anti-Mi-2-positive dermatomyositis patient.A: Proximal upper-arm adipose atrophy with prominence of muscular and bony contours.B: Facial lipoatrophy with loss of volume in the cheeks, perioral region, and jawline, accentuating nasolabial folds.C: Symmetrical reduction of subcutaneous adipose tissue in the femoral region.D: Bilateral gluteal lipoatrophy with decreased contour and loss of adipose prominence.The distribution pattern is symmetrical and cephalocaudal, typical of acquired lipodystrophy in inflammatory myopathies.

Fields of Study & Subjects

Inflammatory Myopathies and Dermatomyositis Systemic Sclerosis and Related Diseases Myasthenia Gravis and Thymoma

Publication details

Journal / source
Clinical and Experimental Rheumatology
Volume
44
Issue
2
Pages
425–426
Publication date
24 February 2026
Language
EN