Effects of physical activity in pediatric acute lymphoblastic leukemia after oncologic treatment
Abstract
Acute lymphoblastic leukaemia (ALL) is the most common paediatric malignancy. Although survival rates have improved, children and survivors frequently experience long-term impairments in aerobic capacity, muscle strength, functional mobility, and health-related quality of life (HRQoL). Objective: To systematically synthesize evidence regarding the effects of structured physical activity and exercise programs in paediatric patients with ALL after oncologic treatment or during late phases of therapy. A systematic review was conducted following PRISMA 2020 and the PICO framework. PubMed, PEDro, and SciELO were searched (September–December 2025). Randomized controlled trials (RCTs), non-randomized trials, and pre–post studies in participants
Fields of Study & Subjects
Childhood Cancer Survivors' Quality of Life
Acute Lymphoblastic Leukemia research
Cancer survivorship and care
Publication details
- Journal / source
- Physical Activity Exercise and Cancer
- Volume
- 3
- Issue
- 1
- Pages
- 25–25
- Publication date
- 4 March 2026
- Language
- EN