Bismuth molybdate nanostructure modified carbon paste electrode for voltammetric sensing of levodopa in the presence of acetaminophen

In the present work, a voltammetric sensor for levodopa (L-DOPA) was fabricated based on Bi2MoO6 nanostructure-modified carbon paste electrodes (Bi2MoO6/CPE). Bi2MoO6 nanostructures were synthesized via the solvothermal procedure and characterized by X-ray diffraction pattern. The Bi₂MoO₆/CPE exhibited an enhanced current response for L-DOPA, which we attribute to the good electrocatalytic activity of the Bi2MoO6 nanostructures. Furthermore, the Bi2MoO6/CPE sensor was applied to determine L-DOPA in the presence of acetaminophen (ACT). The anodic peaks for L-DOPA and ACT were well-resolved in their mixture, enabling their simultaneous determination. The voltammetric measurements at pH 7.0 revealed distinct anodic peaks for the two analytes, located at approximately 350 mV (L-DOPA) and 530 mV (ACT). Using differential pulse voltammetry, a linear correlation was observed between the oxidation peak current and L-DOPA concentration over the range 0.02 to 590.0 μM. The limit of detection was determined to be 0.009 μM. The practical applicability of the Bi2MoO6/CPE sensor was successfully demonstrated through the assay of L-DOPA and ACT in real samples.