The use of a combination of betamethasone dipropionate and salicylic acid in the treatment of inflammatory dermatoses

Combined preparations are commonly used in the topical treatment of many inflammatory skin diseases. The simultaneous use of two substances with different mechanisms of action can produce an additive effect, thereby increasing their effectiveness. Topical glucocorticosteroids are the basis of the treatment for many inflammatory, autoimmune, allergic, or hyperproliferative dermatological conditions. Betamethasone dipropionate is a potent glucocorticosteroid receptor agonist, classified as class III according to the World Health Organization (WHO) classification. Salicylic acid has keratolytic and anti-inflammatory properties and stimulates the regeneration process. Exfoliation of keratinocytes from areas affected by hyperkeratosis with the help of salicylic acid promotes the penetration of active substances deep into the skin, directly to the sites of disease. The application of a combination preparation containing both betamethasone dipropionate and salicylic acid increases the effectiveness of pharmacotherapy for many inflammatory dermatoses, with particular emphasis on dermatological conditions with hyperproliferation.