Doughnut wart formation after cryotherapy of viral wart in a patient with alopecia areata

Doughnut warts are a rare recurrence pattern characterized by central clearance with peripheral regrowth following treatment of viral warts. Although typically associated with destructive modalities such as cryotherapy, their development may be influenced by underlying immune dysregulation. Alopecia areata (AA), while clinically confined to hair-bearing areas, is increasingly recognized as a condition with systemic immunological alterations that may affect cutaneous antiviral responses. This case report describes the occurrence of a doughnut wart after cryotherapy in a patient with AA and highlights the potential role of autoimmune-related immune imbalance in shaping atypical wart behavior. Understanding this relationship may help guide clinicians toward selecting treatment approaches that reduce recurrence risk in patients with immune-mediated skin conditions.