Anemia: an uncommon cause of cerebral venous sinus thrombosis

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Authors: Iqra Athar, Afrah Malik, Neelma Naz Khattak, Tashfain Shifa, Zukhruf Zayian
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Abstract

Cerebral venous sinus thrombosis (CVST) is a multifactorial illness seen more commonly in females as compared to males. Its diagnosis is often delayed due to variable clinical presentations. It is now identified more often due to advancements in neuroimaging modalities. We present an uncommon case of CVST caused by anemia in a 23-year-old female. Our patient presented with complaints of headache since the past two days and left sided hemiplegia since past one day. Later on during her hospital stay she developed generalized tonic clonic seizures. MRI and MRV brain with contrast revealed right cerebral venous (vein of Trolard) thrombosis. Blood tests showed hypochromic microcytic anemia which was the likely precipitating factor in our case as thrombophilia factors were normal. Headache and focal neurological symptoms should raise suspicion of CVST in anemic patients. Early commencement of anticoagulation along with correction of underlying cause, anemia in this case, leads to better prognosis.

Fields of Study & Subjects

Cerebral Venous Sinus Thrombosis Neurosurgical Procedures and Complications Vascular Malformations Diagnosis and Treatment

Publication details

Journal / source
Pakistan Journal of Neurological Sciences
Volume
20
Issue
01
Publication date
1 January 2026
Language
EN