The Effect of Malaria on Serum Electrolyte Levels among Pregnant Women Attending Mubi General Hospital, Adamawa State, Nigeria

Malaria in pregnancy remains a major public health concern in sub-Saharan Africa, associated with maternal anemia, low birth weight, and mortality. This study aimed to determine the effect of malaria infection on serum electrolyte levels (sodium, potassium, chloride, and bicarbonate) among pregnant women attending Mubi General Hospital. A hospital-based comparative cross-sectional study was conducted from July to October 2025. A total of 180 pregnant women were enrolled. Rapid diagnostic test (RDT) and microscopy were used for the detection of malaria parasites, and for electrolyte analysis using an automated electrolyte analyzer. Socio-demographic and obstetric data were obtained via a structured questionnaire. Data were analyzed using appropriate tools. The mean serum levels of sodium (Na⁺), potassium (K⁺), and bicarbonate (HCO₃⁻) were significantly lower in the malaria-infected group compared to controls (Na⁺: 132.1 ± 5.2 vs. 138.5 ± 3.8 mmol/L, p