Total Pancreatectomy and Islet Auto Transplantation in South Australia: A Preliminary Evaluation of a 10‐Year Experience

The Medical Journal of Australia 2026 Open access

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Authors: Gorjana Radisic, Colleen Etherton, Alice Rickard, Merle Weetra, Denghao Wu, Sanjeev Khurana, Bhanu Mariyappa Rathnamma, Jenny Harrington, Tom Loudovaris, Gordon Thomas, Henry C. C. Pleass, Alex Brown
+6 more Twh Kay, Chris Drogemuller, David James Torpy, Richard T L Couper, J W C Chen, Patrick Toby Coates
DOI: 10.5694/mja2.70129
Cited by: 0
References: 10

Abstract

Hereditary pancreatitis causes severe early-onset pain and hospitalisation. In 15 Australian patients undergoing total pancreatectomy and islet auto transplantation (TPIAT), we observed a marked reduction in hospital admissions, inpatient days and emergency visits, complete analgesic cessation by 24 months and durable insulin independence in nearly half of the patients. These findings highlight TPIAT's potential to improve quality of life and reduce healthcare burden. Our programme aims to build evidence to support public funding and ensure equitable access to this procedure.

Fields of Study & Subjects

Pancreatitis Pathology and Treatment Pancreatic function and diabetes Pancreatic and Hepatic Oncology Research

Publication details

Journal / source
The Medical Journal of Australia
Volume
224
Issue
1
Pages
e70129–e70129
Publication date
1 January 2026
Language
EN