Impact of Oral Food Challenge (OFC) in daily activities and quality of life in children with IGE-Mediated food allergy

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Authors: Azwin Mengindra Putera, Hilya Mirats Rozana, Irwanto Irwanto
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Abstract

To analyze the impact of food allergies on daily activities and the quality of life in children with food allergies by OFC.Methods: This study provides an overview of the types of food that because allergies based on the results of the Skin Prick Test, Elimination diet, Oral Food Challenge (OFC) performed to confirm a suspected food allergy diagnosis, Daily activities (The Food Allergy Impact Scale / FAIS), Quality of life (uses the pediatric quality of life inventory/ PedsQL) at the Allergy Polyclinic, Department of Pediatrics, Dr. Soetomo Hospital.In this study, the participants were dominated by boys, 65.6%.Most participants were 0-5 years old, 47.2%.Based on the FAIS pre and post-OFC test, there were significant differences with p-value = .000in meal preparation, family social activities, caregiver stress and free time, autonomous child social activities, employment and finances, and p-value = .001in caregiver-supervised child social activities.In assessing PedsQL, there is a significant difference before and after OFC with a p-value = .000in all health domains.The results of the skin prick test on several types of food, the most positive skin prick test results were found in freshwater fish species was 149 patients (71.3%).In the OFC, the highest positive results for several types of food were cow's milk, 77 children (36.8%), and chocolate, 76 children (36.4%).The OFC procedure is necessary for managing food allergies because it improves daily family activities and the quality of life in children with food allergies.

Fields of Study & Subjects

Food Allergy and Anaphylaxis Research Eosinophilic Esophagitis Drug-Induced Adverse Reactions

Publication details

Journal / source
Perinatal Journal
Volume
34
Issue
1
Publication date
1 January 2026