Diagnosis problems in patients with chronic teraparsec

Tetraparesis is a condition of motor weakness of the four extremities that can indicate a serious neurological disorder.The case reported a 27-year-old woman with progressive weakness in her shoulder and thigh muscles for five months.The purpose of this study is to establish the comparative diagnosis of tetraparesis and determine its etiology through clinical, laboratory, radiology, and histopathological approaches.The research method used a case study approach with comprehensive examinations including electromyography (EMG), Magnetic Resonance Imaging (MRI), myopathy serology profile, and muscle biopsy.The results of the examination showed an increase in muscle enzymes (SGOT, SGPT, creatinine kinase), myositis-specific antibodies (NXP2 and SRP positive), and endomisal lymphocyte infiltration on muscle biopsy that supported the diagnosis of Idiopathic Inflammatory Myopathy subtype polymyositis.Patients showed significant clinical improvement after intravenous methylprednisolone therapy of 500 mg for three days and cyclophosphamide 500 mg of single dose.The discussion emphasized the importance of differentiating the etiology of tetraparesis between central, peripheral, and myopathic lesions to determine the appropriate management.In conclusion, early diagnosis and aggressive immunomodulatory therapy play an important role in preventing permanent disability as well as improving the prognosis of patients with polymyositis.