Primary Cell Isolation from Solid Tissues and Current Understanding for Their Application in Personalized Medicine and Drug Development

Cells isolated from solid healthy or cancer tissues can provide more accurate and reliable information about the biology of the disease and thus can direct personalized cancer therapy. Cell cultures established from primary cells can model the in-vivo tissue biology, physiology and 3D structure. Nowadays, with the advancement of science and technology and the recognition of the importance of personalized medicine, the use of primary cell lines is increasingly coming to the forefront. Primary cells isolated from patients can be used in personalized medicine to establish patients’ specific treatments in cancer, neurological disorders and other diseases. Also, these cells can form the base of cell therapies, new drug target identifications and drug developments.