A new chronic larval bioassay using the wild marine shrimp Palaemon serratus, integrating inter-female variability and non-monotonic dose-responses

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Authors: Jason Jeanne, Benoît Xuereb, Aurélie Siberchicot, Marie Laure Delignette‐Muller, Élise Billoir, Romain Coulaud
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Abstract

Larvae of Palaemon serratus were obtained from 4 females and reared under controlled laboratory conditions. Larval groups were exposed from hatching until the end of the larval period (metamorphosis or end of observation) to a concentration gradient of fenoxycarb, including a control (9 dose levels; static renewal). Developmental progression was monitored at predefined intervals (3 times/week), and the timing of developmental events was recorded. Stage-transition times were stored as time-to-event data (TTE) and treated as censored when a transition was not observed within the follow-up window. The time to metamorphosis (TTM) was recorded similarly and treated as censored when metamorphosis did not occur during the observation period. Metamorphosis success was also coded as a binary endpoint (success/failure). In addition, continuous endpoints related to body weight (at hatching and/or juvenile) and energy reserves were measured according to the associated laboratory protocols. The deposited datasets correspond to the following: Data_Binary (metamorphosis success); Data_Censored_TTE (censored time-to-stage transition); Data_Censored_TTM (censored time-to-metamorphosis); Data_Continu_Energy (continuous energy-related endpoints); Data_Continu_Weight (continuous weight endpoints); Data_Continu_Weight_Hatching (baseline weight at hatching); and Data_Kaplan_Meier (Kaplan–Meier-ready tables: time, event indicator, treatment group and identifiers).

Fields of Study & Subjects

Environmental Toxicology and Ecotoxicology Crustacean biology and ecology Effects and risks of endocrine disrupting chemicals

Publication details

Journal / source
Recherche Data Gouv France
Publication date
1 January 2026
Language
EN
Document type
Dataset