Mechanism Study of Chlorogenic Acid and L. reuteri in Synergistically Ameliorating Ulcerative Colitis

ScienceDB 2026 Dataset Open access

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Authors: Jiaxin You
DOI: 10.57760/sciencedb.27717
Cited by: 0

Abstract

Supplementation with L. reuteri significantly enhances the utilization of chlorogenic acid by the gut microbiota in UC mice.Chlorogenic acid and L. reuteri exert synergistic anti-inflammatory effects through the JAK1/STAT3 pathway.p-Coumaric acid and dihydrocaffeic acid are key metabolites of chlorogenic acid in inhibiting inflammation.

Fields of Study & Subjects

Gut microbiota and health Inflammatory Bowel Disease Probiotics and Fermented Foods

Publication details

Journal / source
ScienceDB
Publication date
24 February 2026
Language
EN
Document type
Dataset