Suilysin of Streptococcus suis serotype 2 drives astrocyte pyroptosis via activation of the ROS/NLRP3/caspase-1/GSDMD pathway

ScienceDB 2026 Dataset Open access

Read full text
Authors: Ruicheng Yang, Lang Tian, Jundan Wang, Wenquan Ouyang, Huanchun Chen, Xiangru Wang
DOI: 10.57760/sciencedb.37136
Cited by: 0

Abstract

This dataset contains raw experimental data supporting the study "Suilysin of Streptococcus suis serotype 2 drives astrocyte pyroptosis via ROS/NLRP3/caspase-1/GSDMD pathway"—including SLY-induced pyroptosis metrics (LDH, IL-1β) in U251 cells (dose/time-dependent), ROS production data, in vivo astrocyte pyroptosis results (P1/7 vs P1/7-Δsly), and raw data for the article’s graphs/statistics (means, SDs). These data enable replication of the study’s key findings.

Fields of Study & Subjects

Inflammasome and immune disorders Streptococcal Infections and Treatments Bacterial Infections and Vaccines

Publication details

Journal / source
ScienceDB
Publication date
6 February 2026
Language
EN
Document type
Dataset